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1

Distinct properties of fenretinide and CD437 lead to synergistic responses with chemotherapeutic reagents

Penny E. Lovat, Marco Ranalli, Francesca Bernassola, Mike Tilby, Archie J. Malcolm, Andy D.J. Pearson, Mauro Piacentini, Gerry Melino, Christopher P.F. Redfern

Journal:

Pediatric Blood & Cancer

Year:

2000

Language:

english

File:

PDF, 211 KB

english, 2000

2

Apoptosis in neuroblastomas induced by interferon-γ involves the CD95/CD95L pathway

Margherita Annicchiarico-Petruzzelli, Francesca Bernassola, Penny E. Lovat, Christopher P.F. Redfern, Andrew D.J. Pearson, Gerry Melino

Journal:

Pediatric Blood & Cancer

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

3

Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs

Penny E. Lovat, Marco Ranalli, Francesca Bernassola, Mike Tilby, Archie J. Malcolm, Andy D.J. Pearson, Mauro Piacentini, Gerry Melino, Christopher P.F. Redfern

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 306 KB

english, 2000

4

Retinoid signalling and gene expression in neuroblastoma cells: RXR agonist and antagonist effects on CRABP-II and RARβ expression

Quentin Campbell Hewson, Penny E. Lovat, Andrew D.J. Pearson, Christopher P.F. Redfern

Journal:

Journal of Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 255 KB

english, 2002

5

Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma

Penny E. Lovat, Marco Ranalli, Marco Corazzari, Lizzia Raffaghello, Andy D.J. Pearson, Mirco Ponzoni, Mauro Piacentini, Gerry Melino, Christopher P.F. Redfern

Journal:

Journal of Cellular Biochemistry

Year:

2003

Language:

english

File:

PDF, 336 KB

english, 2003

6

The Kupffer cell in experimental extrahepatic cholestasis in the rat—a light microscopy, immunohistochemical and electron microscopy study

D. St. John Collier, James A. Pain, Derek G. D. Wight, Penny Lovat, Michael E. Bailey

Journal:

The Journal of Pathology

Year:

1986

Language:

english

File:

PDF, 648 KB

english, 1986

7

Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours

Jane L. Armstrong, Gareth J. Veal, Christopher P. F. Redfern, Penny E. Lovat

Journal:

Year:

2007

Language:

english

File:

PDF, 656 KB

english, 2007

8

Molecular Mechanisms of Fenretinide-Induced Apoptosis of Neuroblastoma Cells

PENNY E. LOVAT, MARCO CORAZZARI, BOJIDAR GORANOV, MAURO PIACENTINI, CHRISTOPHER P. F. REDFERN

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 2.36 MB

english, 2004

9

9-cis retinoic acid — a better retinoid for the modulation of differentiation, proliferation and gene expression in human neuroblastoma

Penny E. Lovat, Helen Irving, Archie J. Malcolm, Andrew D.J. Pearson, Christopher P.F. Redfern

Journal:

Journal of Neuro-Oncology

Year:

1997

Language:

english

File:

PDF, 126 KB

english, 1997

10

Differential activation of the aryl hydrocarbon receptor and regulation of differentiation in the epidermal equivalent model

Alison R. Forrester, Penny E. Lovat, Mark Graham, Faith M. Williams, Nick J. Reynolds

Journal:

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

11

Effector Mechanisms of Fenretinide-Induced Apoptosis in Neuroblastoma

Penny E. Lovat, Marco Ranalli, Margherita Annichiarrico-Petruzzelli, Francesca Bernassola, Mauro Piacentini, Archie J. Malcolm, Andy D.J. Pearson, Gerry Melino, Christopher P.F. Redfern

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 243 KB

english, 2000

12

Fenretinide: A p53-independent way to kill cancer cells

Marco Corazzari, Penny E. Lovat, Serafina Oliverio, Federica Di Sano, Raffaele Perrone Donnorso, Christopher P.F. Redfern, Mauro Piacentini

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 250 KB

english, 2005

13

The role of gangliosides in fenretinide-induced apoptosis of neuroblastoma

Penny E. Lovat, Marco Corazzari, Federica Di Sano, Mauro Piacentini, Christopher P.F. Redfern

Journal:

Year:

2005

Language:

english

File:

PDF, 101 KB

english, 2005

14

Differential effects of retinoic acid isomers on the expression of nuclear receptor co-regulators in neuroblastoma

Penny E Lovat, Margherita Annicchiarico-Petruzzelli, Marco Corazzari, Mark G Dobson, Archie J Malcolm, Andy D.J Pearson, Gerry Melino, Christopher P.F Redfern

Journal:

Year:

1999

Language:

english

File:

PDF, 239 KB

english, 1999

15

The effects of anesthesia and surgery on lymphocyte populations and function in infants and children

Martin P. Ward Platt, Penny E. Lovat, J. Graham Watson, A. Aynsley-Green

Journal:

Journal of Pediatric Surgery

Year:

1989

Language:

english

File:

PDF, 365 KB

english, 1989

16

Induction of GADD153 and Bak: novel molecular targets of fenretinide-induced apoptosis of neuroblastoma

Penny E. Lovat, Serafina Oliverio, Marco Corazzari, Marco Ranalli, Andy D.J. Pearson, Gerry Melino, Mauro Piacentini, Christopher P.F. Redfern

Journal:

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

17

Targeting GRP78 to enhance melanoma cell death

Shaun Martin, David S. Hill, James C. Paton, Adrienne W. Paton, Mark A. Birch-Machin, Penny E. Lovat, Chris P.F. Redfern

Journal:

Pigment Cell & Melanoma Research

Year:

2010

Language:

english

File:

PDF, 369 KB

english, 2010

18

Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications

Corazzari, Marco, Fimia, Gian Maria, Lovat, Penny, Piacentini, Mauro

Journal:

Seminars in Cancer Biology

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

19

Retinoic acid receptor expression during the in vitro differentiation of human neuroblastoma

Lovat, Penny E., Pearson, Andrew D.J., Malcolm, Archie, Redfern, Christopher P.F.

Journal:

Neuroscience Letters

Year:

1993

Language:

english

File:

PDF, 744 KB

english, 1993

20

Concentration-dependent effects of 9-cis retinoic acid on neuroblastoma differentiation and proliferation in vitro

Lovat, Penny E., Lowis, Stephen P., Pearson, Andrew D.J., Malcolm, Archie J., Redfern, Christopher P.F.

Journal:

Neuroscience Letters

Year:

1994

Language:

english

File:

PDF, 343 KB

english, 1994

21

Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma

McKee, Christopher S., Hill, David S., Redfern, Christopher P. F., Armstrong, Jane L., Lovat, Penny E.

Journal:

Experimental Dermatology

Year:

2013

Language:

english

File:

PDF, 325 KB

english, 2013

22

Prognostic Impact of p62 Expression in Cutaneous Malignant Melanoma

Ellis, Robert A, Horswell, Stuart, Ness, Tom, Lumsdon, Jonathan, Tooze, Sharon A, Kirkham, Nigel, Armstrong, Jane L, Lovat, Penny E

Journal:

The Journal of Investigative Dermatology

Year:

2014

Language:

english

File:

PDF, 221 KB

english, 2014

23

Cell-Type Variation in Stress Responses as a Consequence of Manipulating GRP78 Expression in Neuroectodermal Cells

Martin, Shaun, Lovat, Penny E., Redfern, Chris P.F.

Journal:

Journal of Cellular Biochemistry

Year:

2015

Language:

english

File:

PDF, 1.86 MB

english, 2015

24

Fateful music from a talented orchestra with a wicked conductor: Connection between oncogenic BRAF, ER stress, and autophagy in human melanoma

Giglio, Paola, Fimia, Gian Maria, Lovat, Penny E, Piacentini, Mauro, Corazzari, Marco

Journal:

Molecular & Cellular Oncology

Year:

2015

Language:

english

File:

PDF, 783 KB

english, 2015

25

News and Notices

Sprecher, Eli, Ingram, John, Lovat, Penny, Brown, Sara, Nijsten, Tamar, Burden, David, Hollestein, Loes

Journal:

British Journal of Dermatology

Year:

2015

Language:

english

File:

PDF, 337 KB

english, 2015

26

Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?

Hill, David S, Lovat, Penny E, Haass, Nikolas K

Journal:

Melanoma Management

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

27

Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy

Hiscutt, Emma L, Hill, David S, Martin, Shaun, Kerr, Ryan, Harbottle, Andrew, Birch-Machin, Mark, Redfern, Christopher P F, Fulda, Simone, Armstrong, Jane L, Lovat, Penny E

Journal:

The Journal of Investigative Dermatology

Year:

2010

Language:

english

File:

PDF, 2.04 MB

english, 2010

28

The Role of MYCN in the Failure of MYCN Amplified Neuroblastoma Cell Lines to G1 Arrest After DNA Damage

Bell, Emma, Premkumar, Rakesh, Carr, Jane, Lu, Xiaohong, Lovat, Penny E, Kees, Ursula R, Lunec, John, Tweddle, Deborah

Journal:

Year:

2006

Language:

english

File:

PDF, 1.14 MB

english, 2006

29

The role of autophagy in squamous cell carcinoma of the head and neck

Cosway, Benjamin, Lovat, Penny

Journal:

Year:

2016

Language:

english

File:

PDF, 572 KB

english, 2016

30

Serial Study of T Lymphocytes in Childhood Leukemia During Remission

Lovat, Penny E., Robinson, John H., Windebank, Kevin P., Kernahan, Jenny, Watson, J. Graham

Journal:

Pediatric Hematology-Oncology

Year:

1993

Language:

english

File:

PDF, 811 KB

english, 1993

31

Glucagon-like Peptide-1 Protects Pancreatic Beta-cells from Death by Increasing Autophagic Flux and Restoring Lysosomal Function

Zummo, Francesco P, Cullen, Kirsty S, Honkanen-Scott, Minna, Shaw, James AM, Lovat, Penny E, Arden, Catherine

Journal:

Year:

2017

Language:

english

File:

PDF, 2.73 MB

english, 2017

32

Effect of conditioned media from mesenchymal stem cells (MSC-CM) on wound healing using a prototype of a fully humanised 3D skin model

Al-Shaibani, Moyassar B., Dickinson, Anne, Nong-Wang, Xiao, Tulah, Asif S., Lovat, Penny E.

Journal:

Year:

2017

Language:

english

File:

PDF, 74 KB

english, 2017

33

Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma

Wu, Chiao-En, Esfandiari, Arman, Ho, Yi-Hsuan, Wang, Nan, Mahdi, Ahmed Khairallah, Aptullahoglu, Erhan, Lovat, Penny, Lunec, John

Journal:

British Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

34

Established and Emerging Biomarkers in Cutaneous Malignant Melanoma

Verykiou, Stamatina, Ellis, Robert, Lovat, Penny

Journal:

Healthcare (MDPI AG)

Year:

2014

Language:

english

File:

PDF, 108 KB

english, 2014

35

Prognostic Impact of Autophagy Biomarkers for Cutaneous Melanoma

Tang, Diana Y. L., Ellis, Robert A., Lovat, Penny E.

Journal:

Frontiers in Oncology

Year:

2016

Language:

english

File:

PDF, 1.78 MB

english, 2016

36

Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses

Widdrington, John D., Gomez-Duran, Aurora, Pyle, Angela, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Baudouin, Simon V., Rostron, Anthony J., Lovat, Penny E., Chinnery, Patrick F., Simpson, A. J

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 2.74 MB

english, 2018

37

ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma

Wu, Chiao-En, Koay, Tsin, Esfandiari, Arman, Ho, Yi-Hsuan, Lovat, Penny, Lunec, John

Journal:

Year:

2018

Language:

english

File:

PDF, 3.51 MB

english, 2018

38

TP53 mutant cell lines selected for resistance to MDM2 inhibitors retain growth inhibition by MAPK pathway inhibitors but a reduced apoptotic response

Wu, Chiao-En, Koay, Tsin Shue, Ho, Yi-Hsuan, Lovat, Penny, Lunec, John

Journal:

Cancer Cell International

Year:

2019

Language:

english

File:

PDF, 1.87 MB

english, 2019

39

Predictive indicators for revisional surgery in nasal reconstruction after Mohs surgery

Andrew, Tom W., Garioch, Jennifer J., Lovat, Penny E., Moncrieff, Marc D.

Journal:

European Journal of Plastic Surgery

Year:

2020

File:

PDF, 229 KB

2020

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